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Ultrafine Hydrogel Nanoparticles: Synthetic Approach and Therapeutic Application in Living Cells
Author(s) -
Gao De,
Xu Hao,
Philbert Martin A.,
Kopelman Raoul
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200603927
Subject(s) - nanoparticle , nanotechnology , chemistry , computer science , world wide web , materials science
Licensed to kill : A method for obtaining ultrafine hydrophilic polyacrylamide‐based nanoparticles that encapsulate meta ‐tetra(hydroxyphenyl)chlorin ( m THPC) has been developed. Rat C6 glioma cells exposed to infrared light were killed (red) in the presence of the m THPC‐encapsulating nanoparticles while the cells without exposure to light were still alive (green).