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Formation of Vesicular Structures through the Self‐Assembly of a Flexible Bis‐Zwitterion in Dimethyl Sulfoxide
Author(s) -
Schmuck Carsten,
Rehm Thomas,
Klein Katja,
Gröhn Franziska
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200603629
Subject(s) - zwitterion , amphiphile , van der waals force , vesicle , chemistry , dimethyl sulfoxide , alkyl , linker , polar , molecule , polymer chemistry , copolymer , organic chemistry , computer science , polymer , physics , biochemistry , astronomy , membrane , operating system
Small molecule, large structures : The connection of two zwitterionic binding motifs with a lipophilic alkyl linker results in an amphiphilic bis‐zwitterion, which forms self‐assembled vesicles even in polar solutions. The data suggest that two bis‐zwitterions dimerize and then further aggregate to form vesicles, most likely driven by H‐bonding and van der Waals interactions between the linkers.