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Gold(I)‐Catalyzed Annulation of Salicylaldehydes and Aryl Acetylenes as an Expedient Route to Isoflavanones
Author(s) -
Skouta Rachid,
Li ChaoJun
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200603495
Subject(s) - annulation , catalysis , moiety , aryl , chemistry , combinatorial chemistry , atom (system on chip) , organic chemistry , computer science , parallel computing , alkyl
The value of gold ‘n’ rings : An isoflavanone moiety is the key structural feature of many complex natural products. It is now shown that such structures can be generated efficiently and atom economically by the annulation of simple o ‐hydroxybenzaldehydes with alkynes in the presence of a gold(I) catalyst (see scheme).