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Evolving Strategies for Protein Synthesis Converge on Native Chemical Ligation
Author(s) -
Macmillan Derek
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200602945
Subject(s) - native chemical ligation , ligation , chemical ligation , computer science , bridge (graph theory) , data science , computational biology , chemical synthesis , chemistry , biology , medicine , biochemistry , microbiology and biotechnology , in vitro
Build a bridge : Although used widely, certain limitations of popular protein assembly strategies such as native chemical ligation (NCL) have persisted. This highlight presents the results of recent reports that tackle these limitations (see picture). Aux=auxiliary.