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A Rearrangement to a Zirconium–Alkenylidene in the Insertion of Dihalocarbenoids and Acetylides into Zirconacycles
Author(s) -
Thomas Emma,
Dixon Sally,
Whitby Richard J
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200602822
Subject(s) - zirconium , chemistry , combinatorial chemistry , medicinal chemistry , organic chemistry
Sequential insertion of 1‐lithio‐1,1‐dihaloalkanes and lithium acetylides into zirconacyclopentenes and ‐pentanes affords complex bicyclo[3.3.0]octenes and bicyclo[3.3.0]octanes through a novel rearrangement of a zirconium–alkynyl to a zirconate—alkenylidene species (see scheme; Cp=cyclopentadienyl).
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