Premium
A Virus Spotlighted by an Autonomous DNA Machine
Author(s) -
Weizmann Yossi,
Beissenhirtz Moritz K.,
Cheglakov Zoya,
Nowarski Roni,
Kotler Moshe,
Willner Itamar
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200602754
Subject(s) - deoxyribozyme , dna , computational biology , chemistry , bacteriophage , virology , biology , microbiology and biotechnology , biochemistry , escherichia coli , gene
Highly sensitive : Analysis of viral DNA (M13 phage) is possible by using a DNA‐based machine that is fueled by dNTPs and synthesizes DNAzyme reporter units. The DNAzymes mimic peroxidase and lead to a colorimetric or chemiluminescent readout of the analyzed DNA.