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Isolation of Cyclopropenylidene–Lithium Adducts: The Weiss–Yoshida Reagent
Author(s) -
Lavallo Vincent,
Ishida Yutaka,
Donnadieu Bruno,
Bertrand Guy
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200602701
Subject(s) - carbene , adduct , lithium (medication) , reagent , chemistry , luck , medicinal chemistry , organic chemistry , philosophy , catalysis , theology , psychology , psychiatry
Luck is important : In the 1970s, Yoshida and Weiss both had the right cyclopropenium cation precursor. With the right counteranion, they would have isolated the first carbene–lithium adduct (see scheme; C black, N blue, O red, Li pink, B yellow, F green). With the right base and counteranion combination, they would have isolated the first stable free carbene.