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Highly Active Chiral Ruthenium Catalysts for Asymmetric Cross‐ and Ring‐Opening Cross‐Metathesis
Author(s) -
Berlin Jacob M.,
Goldberg Steven D.,
Grubbs Robert H.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200602469
Subject(s) - metathesis , ruthenium , salt metathesis reaction , scope (computer science) , catalysis , ring (chemistry) , combinatorial chemistry , chemistry , ring closing metathesis , enantioselective synthesis , stereochemistry , computer science , organic chemistry , polymerization , programming language , polymer
Metathesis takes sides : The scope of asymmetric metathesis has been expanded with the use of chiral ruthenium catalysts for asymmetric ring‐opening cross‐metathesis and for the first example of an asymmetric cross‐metathesis (see scheme, TIPS=triisopropylsilyl). Information about the mechanism of asymmetric ring‐opening cross‐metathesis should allow the development of more selective catalysts.