Photoswitching of the Fluorescent Protein asFP595: Mechanism, Proton Pathways, and Absorption Spectra | Zendy

Schäfer Lars V. | Zendy; Groenhof Gerrit | Zendy; Klingen Astrid R. | Zendy; Ullmann G. Matthias | Zendy; BoggioPasqua Martial | Zendy; Robb Michael A. | Zendy; Grubmüller Helmut | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Photoswitching of the Fluorescent Protein asFP595: Mechanism, Proton Pathways, and Absorption Spectra

Author(s) -

Schäfer Lars V.,

Groenhof Gerrit,

Klingen Astrid R.,

Ullmann G. Matthias,

BoggioPasqua Martial,

Robb Michael A.,

Grubmüller Helmut

Publication year - 2007

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200602315

Subject(s) - chromophore , isomerization , chemistry , fluorescence , fluorescent protein , proton , molecular switch , cascade , mechanism (biology) , absorption (acoustics) , chemical physics , photochemistry , molecule , green fluorescent protein , physics , organic chemistry , biochemistry , quantum mechanics , chromatography , acoustics , gene , catalysis

Molecular light‐switch : Off–on switching of the fluorescence of the protein asFP595 involves a trans – cis isomerization. Mixed quantum/classical simulations elucidate the spectroscopic properties of asFP595 and give detailed insights into the photoswitching mechanism. The conformational trans – cis switching triggers a proton‐transfer cascade between the chromophore and adjacent amino acids.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research