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A Diaminochlorophosphine for Palladium‐Catalyzed Arylations of Amines and Ketones
Author(s) -
Ackermann Lutz,
Spatz Julia H.,
Gschrei Christian J.,
Born Robert,
Althammer Andreas
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200602222
Subject(s) - steric effects , palladium , aryl , chemistry , catalysis , organic chemistry , combinatorial chemistry , alkyl
Sterically hindered substituents on a secondary chlorophosphine 1 prevent formation of a diaminooxophosphine, and thereby allow for highly efficient arylation reactions of amines and α‐C‐H acidic ketones with (hetero)aryl chlorides.