Enantioselective Total Synthesis and Structure Determination of the Antiherpetic Anthrapyran Antibiotic AH‐1763 IIa | Zendy

Tietze Lutz F. | Zendy; Gericke Kersten M. | Zendy; Singidi Ramakrishna Reddy | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Enantioselective Total Synthesis and Structure Determination of the Antiherpetic Anthrapyran Antibiotic AH‐1763 IIa

Author(s) -

Tietze Lutz F.,

Gericke Kersten M.,

Singidi Ramakrishna Reddy

Publication year - 2006

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200601992

Subject(s) - enantioselective synthesis , diastereomer , antibiotics , stereochemistry , chemistry , natural product , organic chemistry , biochemistry , catalysis

The antiherpetic anthrapyran antibiotic (14 S ,16 R )‐AH‐1763 IIa (see right‐hand structure) and its (14 R ,16 R ) diastereomer have been prepared in enantioselective total syntheses. The relative and absolute stereochemistry of the natural product was established as (14 R ,16 S ), and a general high‐yielding, selective approach to anthrapyran antibiotics was developed.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research