A Bifunctional Molecularly Imprinted Polymer (MIP): Analysis of Binding and Catalysis by a Thermistor | Zendy

Lettau Kristian | Zendy; Warsinke Axel | Zendy; Katterle Martin | Zendy; Danielsson Bengt | Zendy; Scheller Frieder W. | Zendy

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A Bifunctional Molecularly Imprinted Polymer (MIP): Analysis of Binding and Catalysis by a Thermistor

Author(s) -

Lettau Kristian,

Warsinke Axel,

Katterle Martin,

Danielsson Bengt,

Scheller Frieder W.

Publication year - 2006

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200601796

Subject(s) - bifunctional , molecularly imprinted polymer , catalysis , chemistry , molecular imprinting , combinatorial chemistry , polymer , thermistor , organic chemistry , selectivity , electrical engineering , engineering

Binding or catalysis? Both can be distinguished with a molecularly imprinted polymer (MIP) by the different patterns of heat generation. The catalytically active sites, like in the corresponding enzyme, generate a steady‐state temperature increase. Thus, enzyme‐like catalysis and antibody‐analogue binding are analyzed simultaneously in a bifunctional MIP for the first time (see scheme).

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