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A Bifunctional Molecularly Imprinted Polymer (MIP): Analysis of Binding and Catalysis by a Thermistor
Author(s) -
Lettau Kristian,
Warsinke Axel,
Katterle Martin,
Danielsson Bengt,
Scheller Frieder W.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200601796
Subject(s) - bifunctional , molecularly imprinted polymer , catalysis , chemistry , molecular imprinting , combinatorial chemistry , polymer , thermistor , organic chemistry , selectivity , electrical engineering , engineering
Binding or catalysis? Both can be distinguished with a molecularly imprinted polymer (MIP) by the different patterns of heat generation. The catalytically active sites, like in the corresponding enzyme, generate a steady‐state temperature increase. Thus, enzyme‐like catalysis and antibody‐analogue binding are analyzed simultaneously in a bifunctional MIP for the first time (see scheme).