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A Stoichiometric Molecularly Imprinted Polymer for the Class‐Selective Recognition of Antibiotics in Aqueous Media
Author(s) -
Urraca Javier L.,
Hall Andrew J.,
MorenoBondi Maria C.,
Sellergren Börje
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200601636
Subject(s) - molecularly imprinted polymer , stoichiometry , aqueous solution , class (philosophy) , polymer , aqueous medium , molecular imprinting , chemistry , organic chemistry , computer science , selectivity , artificial intelligence , catalysis
Making a good impression : A molecularly imprinted polymer is prepared against Penicillin G by using a stoichiometric quantity of a urea‐based monomer. This polymer displays a high affinity for the template (see picture) and other β‐lactam antibiotics, as determined by chromatographic retention factors in high quantities of buffer (90 %). Retention values on the nonimprinted polymer were dramatically lower under the same conditions.