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Simplified Analysis of Mixtures of Small Molecules by Chromatographic NMR Spectroscopy
Author(s) -
Pages Guilhem,
Delaurent Corinne,
Caldarelli Stefano
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200601622
Subject(s) - magic angle spinning , nuclear magnetic resonance spectroscopy , spectroscopy , high performance liquid chromatography , chromatography , chemistry , molecule , analytical chemistry (journal) , chromatographic separation , magic angle , organic chemistry , physics , quantum mechanics
Break it up : Ordinarily, silica gel produces no separation in a mixture of aromatic molecules by HPLC; however, solid‐enhanced DOSY NMR spectroscopy succeeds in this task, although its separation capabilities concern just the spectral components. Chromatographic NMR spectroscopy may thus prove a simple complement to HPLC in favorable cases. MAS=magic‐angle spinning.