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Luminescence Studies of the Intracellular Distribution of a Dinuclear Gold(I) N‐Heterocyclic Carbene Complex
Author(s) -
Barnard Peter J.,
Wedlock Louise E.,
Baker Murray V.,
BernersPrice Susan J.,
Joyce David A.,
Skelton Brian W.,
Steer James H.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200601526
Subject(s) - luminescence , carbene , denticity , ligand (biochemistry) , cyclophane , chemistry , distribution (mathematics) , fluorescence , stereochemistry , photochemistry , crystallography , materials science , crystal structure , physics , organic chemistry , receptor , optoelectronics , optics , mathematics , mathematical analysis , biochemistry , catalysis
Gold lights the way : A bidentate cyclophane N‐heterocyclic carbene ligand has been used to synthesize a new dinuclear Au I complex of the formula [Au 2 L 2 ] 2+ . The short Au⋅⋅⋅Au distance imposed by the rigid cyclophane ligand leads to a red‐shifted luminescence profile that enables the complex to be used as a luminescent probe for distribution studies in single living cancer cells.