Dinuclear Double‐Stranded Metallosupramolecular Ruthenium Complexes: Potential Anticancer Drugs | Zendy

Hotze Anna C. G. | Zendy; Kariuki Benson M. | Zendy; Han Michael J. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Dinuclear Double‐Stranded Metallosupramolecular Ruthenium Complexes: Potential Anticancer Drugs

Author(s) -

Hotze Anna C. G.,

Kariuki Benson M.,

Han Michael J.

Publication year - 2006

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200601351

Subject(s) - ruthenium , bridge (graph theory) , chemistry , stereochemistry , architecture , twist , computational biology , combinatorial chemistry , computer science , biochemistry , biology , art , mathematics , geometry , catalysis , visual arts , anatomy

Just add a twist : Metallosupramolecular architecture design is used to create anti‐cancer agents with high activities in human breast cancer cell lines. Three isomers, which comprise a nonhelical metallocyclophane, an unsaturated double helicate, and a new type of double helicate, bridge the fields of metallosupramolecular architecture and anticancer drug design (picture: double‐helical trans / cis isomer; red Ru, green Cl).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research