Gold(I)‐Catalyzed Reaction of 1‐(1‐Alkynyl)‐cyclopropyl Ketones with Nucleophiles: A Modular Entry to Highly Substituted Furans | Zendy

Zhang Junliang | Zendy; Schmalz HansGünther | Zendy

Premium

Gold(I)‐Catalyzed Reaction of 1‐(1‐Alkynyl)‐cyclopropyl Ketones with Nucleophiles: A Modular Entry to Highly Substituted Furans

Author(s) -

Zhang Junliang,

Schmalz HansGünther

Publication year - 2006

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200601252

Subject(s) - nucleophile , catalysis , chemistry , ring (chemistry) , modular design , combinatorial chemistry , medicinal chemistry , atom (system on chip) , organic chemistry , computer science , programming language , parallel computing

Ring round : 1‐Acyl‐1‐alkynyl‐cyclopropanes smoothly react with nucleophiles in the presence of a gold(I) catalyst to afford substituted furans in a fully atom‐economical fashion (see scheme; Nu=nucleophile, Tf=trifluoromethanesulfonyl). The reaction tolerates a wide range of substrates.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research