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Thermoresponsive Micelles from Oligopeptide‐Grafted Cyclotriphosphazenes
Author(s) -
Jun Yong Joo,
Toti Udaya S.,
Kim Hye Young,
Yu Ji Young,
Jeong Byeongmoon,
Jun Moo Jin,
Sohn Youn Soo
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200601108
Subject(s) - oligopeptide , micelle , materials science , chemistry , biophysics , peptide , biochemistry , organic chemistry , aqueous solution , biology
Hard graft : Amphiphilic cyclic phosphazene trimers grafted with hydrophobic oligopeptide (red) and hydrophilic methoxypolyethylene glycol (blue) show a variety of thermoresponsive properties including lower critical solution temperatures near body temperature. They form strong micelles in aqueous solution at an appropriate hydrophobic‐to‐hydrophilic balance.