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Pericyclic Cascade Reactions of (Bicyclo[1.1.0]butylmethyl)amines
Author(s) -
Wipf Peter,
Walczak Maciej A. A.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200600723
Subject(s) - pericyclic reaction , bicyclic molecule , chemistry , cascade , pyrrolidine , stereochemistry , combinatorial chemistry , chromatography
Direct access : Phase‐transfer N ‐allylation and N ‐propargylation of (bicyclo[1.1.0]butylmethyl)amines initiate diastereoselective pericyclic cascade reactions that culminate in novel spirocyclic and tricyclic pyrrolidine heterocycles through formal ene or [2+2] pathways.