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High‐Throughput Carbohydrate Microarray Analysis of 24 Lectins
Author(s) -
Manimala Joseph C.,
Roach Timothy A.,
Li Zhitao,
Gildersleeve Jeffrey C.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200600591
Subject(s) - lectin , carbohydrate , microarray , computational biology , throughput , microarray analysis techniques , gene chip analysis , dna microarray , chemistry , biology , biochemistry , computer science , gene , gene expression , telecommunications , wireless
Hip hip array : Lectins are involved in a wide range of biological processes and are used frequently as tools for basic and applied research. Through the use of a carbohydrate microarray, high‐throughput analysis of lectin specificity was carried out on 24 different lectins. Many of the carbohydrate ligands identified for the lectins were unexpected based on previous information.