Self‐Assembled Signaling Aptamer DNA Arrays for Protein Detection | Zendy

Lin Chenxiang | Zendy; Katilius Evaldas | Zendy; Liu Yan | Zendy; Zhang Junping | Zendy; Yan Hao | Zendy

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Self‐Assembled Signaling Aptamer DNA Arrays for Protein Detection

Author(s) -

Lin Chenxiang,

Katilius Evaldas,

Liu Yan,

Zhang Junping,

Yan Hao

Publication year - 2006

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200600438

Subject(s) - aptamer , dna , fluorescence microscope , confocal microscopy , nanotechnology , confocal , fluorescence , biosensor , tile , dna microarray , chemistry , protein detection , biophysics , microbiology and biotechnology , materials science , biology , biochemistry , gene , gene expression , physics , geometry , mathematics , quantum mechanics , composite material

Sticking the tiles : A DNA‐tile‐directed self‐assembly of signaling aptamers into high‐density nanoarrays allows subnanomolar detection of protein molecules by using confocal fluorescence microscopy imaging. This water‐soluble aptamer microarray provides a novel strategy for developing programmable sensor arrays.

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