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Orthogonal Glycosylation Reactions on Solid Phase and Synthesis of a Library Consisting of a Complete Set of Fucosyl Galactose Isomers
Author(s) -
Kanie Osamu,
Ohtsuka Isao,
Ako Takuro,
Daikoku Shusaku,
Kanie Yoshimi,
Kato Rumiko
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200600433
Subject(s) - glycosylation , set (abstract data type) , sequence (biology) , computer science , scheme (mathematics) , chemistry , combinatorial chemistry , information retrieval , stereochemistry , mathematics , biochemistry , programming language , mathematical analysis
A dream team : Orthogonal glycosylation and solid‐phase synthesis were shown to be an excellent combination for polysaccharide synthesis (see scheme). The method was applied to generate a complete library of structural isomers with an L ‐fucosyl‐ D ‐galactose sequence.