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Reactive Polymer Coatings that “Click”
Author(s) -
Nandivada Himabindu,
Chen HsienYeh,
Bondarenko Lidija,
Lahann Joerg
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200600357
Subject(s) - click chemistry , biomolecule , polymer , cycloaddition , azide , nanotechnology , biosensor , gas phase , chemistry , combinatorial chemistry , materials science , computer science , organic chemistry , catalysis
Everything just clicks into place : Alkyne‐group functionalized polymer films that are deposited from the gas phase allow spatially defined immobilization of biomolecules, such as biotin, through the 1,3‐dipolar cycloaddition click reaction with azide derivatives (see scheme). Such biofunctional surfaces have applications in diagnostics and biosensors.