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Multiplexed DNA Detection with Biobarcoded Nanoparticle Probes
Author(s) -
Stoeva Savka I.,
Lee JaeSeung,
Thaxton C. Shad,
Mirkin Chad A.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200600124
Subject(s) - multiplexing , nanoparticle , dna , nanotechnology , computational biology , computer science , materials science , biology , genetics , telecommunications
Sorting the mail : A highly selective assay for the detection of multiple DNA targets in solution was developed based on gold nanoparticles with oligonucleotide reporters. Four DNA targets associated with infectious viruses were detected simultaneously without enzymatic amplification at mid‐femtomolar concentrations.