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Cover Picture: Ruthenium‐Catalyzed Asymmetric Propargylic Substitution Reactions of Propargylic Alcohols with Acetone (Angew. Chem. Int. Ed. 47/2005)
Author(s) -
Inada Youichi,
Nishibayashi Yoshiaki,
Uemura Sakae
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200590156
Subject(s) - ruthenium , moiety , chemistry , acetone , ring (chemistry) , catalysis , nucleophilic substitution , cover (algebra) , nucleophile , medicinal chemistry , combinatorial chemistry , organic chemistry , mechanical engineering , engineering
Diruthenium complexes with optically active thiolate‐bridged ligands promote the catalytic propargylic substitution of propargylic alcohols with acetone as the nucleophile. The use of novel chiral ligands bearing a phenyl ring that can engage in a π–π interaction with a phenyl ring of the ruthenium–allenylidene moiety lead to high enantioselectivities in these processes. For more details, see the Communication by Y. Nishibayashi and co‐workers on page 7715 ff.