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Cover Picture: CuH in a Bottle: A Convenient Reagent for Asymmetric Hydrosilylations (Angew. Chem. Int. Ed. 39/2005)
Author(s) -
Lipshutz Bruce H.,
Frieman Bryan A.
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200590130
Subject(s) - reagent , enantioselective synthesis , catalysis , chemistry , int , cover (algebra) , combinatorial chemistry , organic chemistry , computer science , engineering , operating system , mechanical engineering
The innate stability of the extraordinarily reactive and enantioselective reagent [{( R )‐(−)‐DTBM‐segphos}CuH] (whose structure is shown in the cover picture) is revealed in the Communication by Lipshutz and Frieman on page 6345 ff. Although there have been many advances in ligand‐accelerated catalysis of hydrosilylations, these reactions invariably require the preparation of the catalyst prior to use owing to their limited shelf‐life. This new reagent represents the first asymmetric “CuH in a Bottle”.