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Cover Picture: Nanoparticle PCR: Nanogold‐Assisted PCR with Enhanced Specificity (Angew. Chem. Int. Ed. 32/2005)
Author(s) -
Li Haikuo,
Huang Jiehuan,
Lv Junhong,
An Hongjie,
Zhang Xiaodong,
Zhang Zhizhou,
Fan Chunhai,
Hu Jun
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200590108
Subject(s) - colloidal gold , nanoparticle , int , chemistry , cover (algebra) , microbiology and biotechnology , dna , nanotechnology , computational biology , biology , materials science , biochemistry , computer science , engineering , mechanical engineering , operating system
Favorable binding of gold nanoparticles to single‐stranded DNA decreases the likelihood of mispair formation during annealing and clearly increases the specificity and yield of PCR, one of the most important standard methods of molecular biology. In their Communication on pp. 5100 ff., Z. Zhang, C. Fan, J. Hu, and co‐workers report on this promising field of biotechnology. (Xiaobin Wang assisted in the production of this image.)