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Laser‐Induced Release of Encapsulated Materials inside Living Cells
Author(s) -
Skirtach Andre G.,
Muñoz Javier Almudena,
Kreft Oliver,
Köhler Karen,
Piera Alberola Alicia,
Möhwald Helmuth,
Parak Wolfgang J.,
Sukhorukov Gleb B.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200504599
Subject(s) - polymer , laser , polyelectrolyte , nanotechnology , microsphere , materials science , biophysics , chemistry , chemical engineering , optics , biology , composite material , physics , engineering
Escape route : The laser‐initiated release of fluorescently labeled polymers from polyelectrolyte‐multilayer microcapsules is demonstrated inside living cancer cells. A polymer is incorporated in capsules with metal nanoparticles in their walls, which serve as light‐absorbing centers. The capsules are internalized by cells and near‐infrared light ruptures the walls of the capsules, thus releasing the content into the cells.