Premium
Siphonazole, an Unusual Metabolite from Herpetosiphon sp.
Author(s) -
Nett Markus,
Erol Özlem,
Kehraus Stefan,
Köck Matthias,
Krick Anja,
Eguereva Ekaterina,
Neu Edith,
König Gabriele M.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200504525
Subject(s) - shikimate pathway , metabolite , polyketide , biosynthesis , stereochemistry , amino acid , amino acid metabolism , bacteria , biochemistry , biology , metabolism , shikimic acid , chemistry , aromatic amino acids , genetics , enzyme
Deep and complex : The first representative (see picture) of a new structural class has been isolated from a deep‐rooted filamentous bacterium of the genus Herpetosiphon. Feeding with 13 C and 15 N‐labeled precursors showed the complex biosynthesis to involve shikimate, the polyketide, and the amino acid metabolism.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom