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“Green” Oxidation Catalysis for Rapid Deactivation of Bacterial Spores
Author(s) -
Banerjee Deboshri,
Markley Andrew L.,
Yano Toshihiro,
Ghosh Anindya,
Berget Peter B.,
Minkley Edwin G.,
Khetan Sushil K.,
Collins Terrence J.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200504511
Subject(s) - cationic polymerization , spore , chemistry , catalysis , pulmonary surfactant , photochemistry , combinatorial chemistry , microbiology and biotechnology , organic chemistry , biochemistry , biology
A view to a kill : Iron(III)‐coordinated tetraamide macrocyclic ligands (see example) activate peroxides in water in the presence of a cationic surfactant to rapidly deactivate spores of the common anthrax surrogate, Bacillus atrophaeus. A 99. % kill can be achieved in 15 min at pH 10 and room temperature with tert ‐butyl hydroperoxide (see TEM images).