Premium
Regio‐ and Stereoselective Decarbonylative Carbostannylation of Alkynes Catalyzed by Pd/C
Author(s) -
Nakao Yoshiaki,
Satoh Jun,
Shirakawa Eiji,
Hiyama Tamejiro
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200504283
Subject(s) - stereoselectivity , propargyl , electrophile , aryl , chemistry , nucleophile , catalysis , alkyne , palladium , medicinal chemistry , stereochemistry , organic chemistry , alkyl
Out with the CO : The highly regio‐ and stereoselective aryl‐, alkenyl‐, and alkylstannylation of alkynes was achieved by the decarbonylative carbostannylation of propargyl 2‐furoates in the presence of Pd/C. Various functionalized alkenylstannanes were obtained that contain nucleophilic alkenylstannane and electrophilic allyl furoate moieties, which can be transformed by coupling reactions.