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Synthesis of a “Half”‐Parent Phosphasilene R 2 SiPH and Its Metalation to the Corresponding P ‐Zinciophosphasilene [R 2 SiPM]
Author(s) -
Driess Matthias,
Block Stefan,
Brym Markus,
Gamer Michael T.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200504145
Subject(s) - tetramethylethylenediamine , metalation , dimethylzinc , center (category theory) , chemistry , content (measure theory) , phosphorus , medicinal chemistry , stereochemistry , computer science , crystallography , organic chemistry , mathematics , catalysis , mathematical analysis
Remarkably stable —even with a hydrogen atom at the low‐coordinate phosphorus center! A straightforward synthesis provides the thermally robust phosphasilenes ( E )/( Z )‐ 1 , which have a terminal PH group. These compounds can be cleanly metalated with dimethylzinc in the presence of tmeda (tetramethylethylenediamine) to afford exclusively the P ‐zincio‐substituted phosphasilene 2 with E configuration. R=2,4,6‐triisopropylphenyl.