Modulation of DNA Constraints That Control Macromolecular Folding | Zendy

Miduturu Chandrasekhar V. | Zendy; Silverman Scott K. | Zendy

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Modulation of DNA Constraints That Control Macromolecular Folding

Author(s) -

Miduturu Chandrasekhar V.,

Silverman Scott K.

Publication year - 2006

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200504124

Subject(s) - macromolecule , dna , folding (dsp implementation) , aptamer , rna , control (management) , computational biology , modulation (music) , computer science , variety (cybernetics) , chemistry , biology , biochemistry , physics , gene , engineering , genetics , artificial intelligence , electrical engineering , acoustics

Taking control with DNA : Covalently attached double‐stranded DNA constraints can control the conformations of other macromolecules. A variety of approaches (including competitive ligand–aptamer interactions) were used to modulate the effects of such constraints on the structure of a large RNA molecule.

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