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Mixed Mg/Li Amides of the Type R 2 NMgCl⋅LiCl as Highly Efficient Bases for the Regioselective Generation of Functionalized Aryl and Heteroaryl Magnesium Compounds
Author(s) -
Krasovskiy Arkady,
Krasovskaya Valeria,
Knochel Paul
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200504024
Subject(s) - regioselectivity , aryl , lithium (medication) , magnesium , chemistry , combinatorial chemistry , organic chemistry , catalysis , medicine , alkyl , endocrinology
Two are better than one : Mixed lithium‐magnesium complexes of the type R 2 NMgCl⋅LiCl are kinetically highly active bases that convert a range of polyfunctional aromatic and heteroaromatic substrates into the corresponding magnesiated derivatives with high regioselectivity.