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Rhenium‐ and Aniline‐Catalyzed One‐Pot Annulation of Aromatic Ketones and α,β‐Unsaturated Esters Initiated by CH Bond Activation
Author(s) -
Kuninobu Yoichiro,
Nishina Yuta,
Shouho Makoto,
Takai Kazuhiko
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200503627
Subject(s) - rhenium , indene , chemistry , aniline , catalysis , annulation , organic chemistry , acrylate , benzene , medicinal chemistry , monomer , polymer
Several reaction steps , including CH activation, lead to indene derivatives in good yields in the rhenium‐catalyzed reaction of aromatic ketimines and ethyl acrylate. Indene derivatives can also be obtained by the reactions of aromatic ketones with α,β‐unsaturated esters in the presence of a catalytic rhenium complex and p ‐anisidine (see scheme).