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Pseudo‐Allosteric Recognition of Mandelic Acid with an Enantioselective Coordination Complex
Author(s) -
Heo Jungseok,
Mirkin Chad A.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200503343
Subject(s) - mandelic acid , enantioselective synthesis , allosteric regulation , chelation , chemistry , stereochemistry , fluorescence , molecular recognition , combinatorial chemistry , receptor , catalysis , biochemistry , organic chemistry , molecule , physics , quantum mechanics
The weak‐link approach is used to synthesize a four‐coordinate Cu I complex for the chiral recognition of mandelic acid. The chelation through 2,2′‐bipyridine in a reaction that concomitantly breaks weak CuS links and opens the condensed structure into a 27‐membered macrocycle switches on the complex so it acts as an enantioselective fluorescent receptor.