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Neuron‐Like Tubular Membranes Made of Diblock Copolymer Amphiphiles
Author(s) -
Battaglia Giuseppe,
Ryan Anthony J.
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200503334
Subject(s) - copolymer , membrane , amphiphile , myelin , materials science , corona (planetary geology) , phase (matter) , chemical engineering , solvent , polymer chemistry , molecule , chemistry , organic chemistry , composite material , central nervous system , polymer , biology , biochemistry , neuroscience , astrobiology , venus , engineering
Implications for the nervous system : The formation of polymeric myelin structures was studied at the copolymer/water interface and then elaborated in a dispersed phase. Sun‐like structures formed with a complex multilamellar core and a corona made of short myelins. Myelin growth is solvent‐promoted, in a strong analogy to natural myelins, which have membranes with a higher proportion of fluidizing molecules such as cholesterol.