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3‐Zinciobenzofuran and 3‐Zincioindole: Versatile Tools for the Construction of Conjugated Structures Containing Multiple Benzoheterole Units
Author(s) -
Nakamura Masaharu,
Ilies Laurean,
Otsubo Saika,
Nakamura Eiichi
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200502920
Subject(s) - conjugated system , chemistry , ring (chemistry) , combinatorial chemistry , molecule , phenols , closing (real estate) , organic chemistry , polymer , political science , law
Closing the ring : Thermally stable but reactive 3‐zinciobenzofurans and indoles were synthesized by metalative cyclization of 2‐ynyl phenols or anilines. Furthermore, a variety of extended π‐conjugated molecules were obtained by Pd‐catalyzed cross‐coupling reactions of these heterocycles with mono‐ or polyhalo‐substituted arenes and alkenes (R 2 Hal n ; see scheme; Bn=benzyl).