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Heterogeneous Catalysis with Nickel‐on‐Graphite (Ni/C g ): Reduction of Aryl Tosylates and Mesylates
Author(s) -
Lipshutz Bruce H.,
Frieman Bryan A.,
Butler Tom,
Kogan Vladimir
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200502887
Subject(s) - aryl , nickel , catalysis , trifluoromethanesulfonate , hydride , graphite , palladium , chemistry , organic chemistry , metal , alkyl
How would you reduce an aryl OH group? Traditionally, a palladium catalyst, a mild source of hydride, and a triflate derivative are used in solution. A more modern alternative is presented that is not only economical but heterogeneous as well. Nickel‐on‐graphite (Ni/C g ) is introduced as a very inexpensive catalyst that reduces aryl tosylates and mesylates with excellent functional group tolerance.