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Fast Colorimetric Sensing of Adenosine and Cocaine Based on a General Sensor Design Involving Aptamers and Nanoparticles
Author(s) -
Liu Juewen,
Lu Yi
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200502589
Subject(s) - aptamer , colloidal gold , nanoparticle , dna , adenosine , substrate (aquarium) , nanotechnology , chemistry , colorimetry , combinatorial chemistry , materials science , biochemistry , biology , chromatography , microbiology and biotechnology , ecology
Apt to change color : DNA aptamers have been used to assemble DNA‐functionalized gold nanoparticles to produce highly sensitive and selective colorimetric sensors with an instantaneous color response on addition of a substrate. The general method has been shown for adenosine and cocaine (see picture), but should be applicable to any aptamer of choice.