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Complex Sequence Dependence by Excess‐Electron Transfer through DNA with Different Strength Electron Acceptors
Author(s) -
Manetto Antonio,
Breeger Sascha,
Chatgilialoglu Chryssostomos,
Carell Thomas
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200502551
Subject(s) - electron transfer , electron , base pair , duplex (building) , dna , electron acceptor , electron transport chain , sequence (biology) , chemistry , flavin group , base (topology) , chemical physics , physics , photochemistry , enzyme , biochemistry , mathematics , mathematical analysis , quantum mechanics
An independent jump : Excess electrons move through DNA by using a hopping‐type mechanism in which the pyrimidine bases dT and dC act as ‘stepping stones’. It was shown that GC base pairs, in contrast to AT base pairs, lower the efficiency of the excess‐electron transfer through the duplex. Through the use of the shown DNA hairpins, three different electron acceptors () were investigated with the electron donor, reduced flavin ().
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