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Soluble Lanthanide Salts (LnCl 3 ⋅2 LiCl) for the Improved Addition of Organomagnesium Reagents to Carbonyl Compounds
Author(s) -
Krasovskiy Arkady,
Kopp Felix,
Knochel Paul
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200502485
Subject(s) - lanthanide , chemistry , steric effects , reagent , catalysis , group 2 organometallic chemistry , organic chemistry , organometallic chemistry , combinatorial chemistry , molecule , ion
Easy‐to‐prepare solutions of LnCl 3 ⋅2 LiCl (Ln=La, Ce, Nd) (0.3–0.5 M in THF) are a unique source of soluble lanthanide salts with versatile applications in organic synthesis. These salts can serve as promoters or catalysts for the addition of organometallic compounds to sterically hindered, enolizable or α,β‐unsaturated ketones or imines.