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Bond‐ and Site‐Selective Loss of H Atoms from Nucleobases by Very‐Low‐Energy Electrons (<3 eV)
Author(s) -
Ptasinska Sylwia,
Denifl Stephan,
Scheier Paul,
Illenberger Eugen,
Märk Tilmann D.
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200502040
Subject(s) - thymine , nucleobase , uracil , electron , atomic physics , chemistry , low energy , physics , dna , biochemistry , quantum mechanics
When excess charge is deposited on thymine and uracil by resonant attachment of low‐energy electrons (0–3 eV), H atoms are cleaved exclusively from the N positions. This bond selectivity can be made site selective (N1 vs. N3 position) by properly tuning the electron energy. This conclusion was drawn from experiments with methylated thymine and uracil (see picture) in crossed beam experiments.