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Synthesis of Imides, N ‐Acyl Vinylogous Carbamates and Ureas, and Nitriles by Oxidation of Amides and Amines with Dess–Martin Periodinane
Author(s) -
Nicolaou K. C.,
Mathison Casey J. N.
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200501853
Subject(s) - chemistry , amide , nitrile , organic chemistry
Expanding our synthetic tool repertoire : The DMP‐mediated oxidation of a range of amide substrates has been demonstrated, affording the corresponding imides and N ‐acyl vinylogous carbamates and ureas. Likewise, an array of benzylic and related amines have also been successfully converted into their nitrile counterparts (see scheme; DMP=Dess–Martin periodinane).