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Catalytic Asymmetric Esterification of Ketenes
Author(s) -
Tidwell Thomas T.
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200501849
Subject(s) - ketene , enol , catalysis , yield (engineering) , chemistry , organic chemistry , medicinal chemistry , materials science , metallurgy
Ketene esterification after 100 years: In the latest advance in the esterification of ketenes, Schaefer and Fu described the catalytic asymmetric conversion of 2‐tolyl(ethyl)ketene ( 1 ) and diphenylacetaldehyde to give the enol ester 2 in 99 % yield and 98 % ee (see scheme).
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