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A Sensitive Colorimetric and Fluorescent Probe Based on a Polythiophene Derivative for the Detection of ATP
Author(s) -
Li Chun,
Numata Munenori,
Takeuchi Masayuki,
Shinkai Seiji
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200501823
Subject(s) - fluorescence , derivative (finance) , polythiophene , adenosine triphosphate , adenosine , aqueous solution , detection limit , chemistry , adenosine diphosphate , supramolecular chemistry , combinatorial chemistry , naked eye , biophysics , photochemistry , chromatography , organic chemistry , biochemistry , polymer , conductive polymer , optics , biology , molecule , physics , platelet , platelet aggregation , immunology , financial economics , economics
From amber to red : The water‐soluble polythiophene derivative 1 forms a supramolecular complex with ATP (adenosine triphosphate) through electrostatic and hydrophobic cooperative interactions which results in a color change of the aqueous solution from yellow to pink‐red (see photo; AMP/ADP=adenosine mono‐/diphosphate). Besides naked‐eye detection of ATP, the detection limit may be extended to 10 −8 M by using fluorometry.