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Regioselective Hypervalent‐Iodine( III )‐Mediated Dearomatizing Phenylation of Phenols through Direct Ligand Coupling
Author(s) -
OzanneBeaude Aurélie,
Quideau Stéphane
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200501638
Subject(s) - hypervalent molecule , regioselectivity , chemistry , phenols , ligand (biochemistry) , iodine , coupling (piping) , stereochemistry , phenol , combinatorial chemistry , organic chemistry , catalysis , receptor , biochemistry , mechanical engineering , engineering
Dearomatization : Treatment of phenols and naphthols substituted at the ortho position by a small electron‐donating group D with chlorodiphenyl‐λ 3 ‐iodane leads to their regioselective ortho phenylation to give cyclohexa‐2,4‐dienone derivatives (see scheme). The mechanism of this reaction involves a nonradical direct coupling of the ligands.