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Differential Receptors Create Patterns That Distinguish Various Proteins
Author(s) -
Wright Aaron T.,
Griffin Michael J.,
Zhong Zhenlin,
McCleskey Shawn C.,
Anslyn Eric V.,
McDevitt John T.
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200501137
Subject(s) - receptor , differential (mechanical device) , computational biology , biology , neuroscience , evolutionary biology , genetics , physics , thermodynamics
Pattern formation : Analysis with an array of differential receptors such as 1 rather than specific receptors leads to patterns for various proteins and glycoproteins that can be examined by principal component analysis. This allows for the direct recognition of large substrates for which the creation of synthetic specific receptors would be very difficult.