Premium
C 9 Helices and Ribbons in γ‐Peptides: Crystal Structures of Gabapentin Oligomers
Author(s) -
Vasudev Prema G.,
Shamala Narayanaswamy,
Ananda Kuppanna,
Balaram Padmanabhan
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200501055
Subject(s) - hydrogen bond , chemistry , residue (chemistry) , crystallography , crystal structure , ring (chemistry) , gabapentin , stereochemistry , amino acid residue , amino acid , peptide , molecule , peptide sequence , organic chemistry , biochemistry , medicine , alternative medicine , pathology , gene
Nine is the number : Novel C 9 ‐hydrogen‐bonded structures (in which the hydrogen bonds enclose a ring of nine atoms) are observed in protected di‐ and tetrapeptides formed by the γ‐amino acid residue gabapentin. The structures reveal new families of C 9 helices and ribbons (see structure) in γ‐polypeptides.