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Ubiquitin at Fox Chase (Nobel Lecture)
Author(s) -
Rose Irwin
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200500995
Subject(s) - ubiquitin , microbiology and biotechnology , chemistry , biology , biochemistry , gene
Protein breakdown is an exact, controlled process in which the protein molecule ubiquitin plays a decisive role by binding to a protein and labeling it for breakdown. The cellular mechanisms of this process are widely known today thanks to the work of the 2004 Nobel Laureates Irwin Rose, Avram Hershko, and Aaron Ciechanover. The Laureates report at first hand in their Nobel Lectures.